Cayce is an uncommon, yet distinctive given name of American origin. It is derived from the surname "Cayce," which has several possible sources: it could be a variant spelling of the Old French name "Caice," itself derived from the Germanic elements "kaio" meaning "rejoice" and "-ic" indicating belonging to; or it might originate from English place names like Caysey in Devon or Kayces in Wiltshire. The name Cayce gained some popularity during the early 20th century, possibly due to its association with the famous American psychic Edgar Cayce. However, it remains relatively rare today, adding to its unique appeal.
"Cayce as a given name sees a notable rise and fall over the years, with peaks in popularity around 1981 (17 births) and 2008 (17 births), but it has generally become less common in recent times, with only 5 births recorded in 2021."