Mikele is a name of Italian origin, derived from the Greek name Michael, which means "who is like God?" In Italy, it is often used as a feminine form of Michele, and its popularity has varied over time. In recent years, it has been among the less common names given to newborn girls in Italy.
Mikele as a baby name had a fluctuating popularity over time, with the most births occurring in 1972 and 1993 at nine each, and the least in several years at five each. The total number of babies named Mikele over these years was sixty-five.