Jenene is of American origin, derived from the French given name Jeanne, which itself comes from the Hebrew name Joan, meaning 'God is gracious.' It gained popularity during the 20th century and is often considered a unique alternative to traditional names like Jennifer or Jeanette.
The name Jenene experienced a steady rise and fall in popularity throughout the century, peaking at 24 births in 1960 and dropping to as low as 5 births by 1987. After that, it became quite rare with only a few occurrences each decade until the late 20th century.