Cayce is an uncommon yet distinctive given name, of uncertain origin and meaning. It first gained prominence as a boy's name in the mid-20th century but has since been used for both boys and girls. The name Cayce is often associated with Edgar Cayce, a notable American psychic and self-proclaimed mystic of the early 20th century, which may have contributed to its uniqueness.
"Cayce as a name saw its peak popularity between the late 1970s and mid-1980s, with over 40 births per year occurring during this period. However, since the early 1990s, the usage of Cayce has significantly decreased, with less than 20 births recorded annually in recent years."