Gregory is derived from the Latin name 'Gregorios', which means "vigilant" or "watchful". This classic name has been widely used throughout history, particularly among those of Greek and Byzantine origin. It gained significant popularity in the Middle Ages due to its association with several prominent historical figures such as Pope Gregory I (also known as Saint Gregory the Great), who played a crucial role in the spread of Christianity, and Gregorios Palamas, a Byzantine theologian and saint. The name has also been used by numerous rulers and scholars throughout history, contributing to its enduring popularity and prestige. In English-speaking countries today, Gregory is often abbreviated as Greg or Gregorie.
The name Gregorio experienced two years of notable popularity with five births each in 1956 and 1961, resulting in a total of ten children bearing this name during that period.