Guadalupe is of Spanish origin, derived from the Latin 'vallis' meaning 'valley,' and 'lupus' meaning 'wolf.' It refers to the valley of the Guadalupe River in Spain. The name gained prominence due to its association with the Virgin Mary, who is believed to have appeared at a location known as Guadalupe in Mexico.
"Guadalupe was a popular name for newborns between 1950 and 1955, with the highest number of babies named Guadalupe born in 1951. Over these six years, there were a total of 27 babies named Guadalupe."