Dereginald is of African origin, derived from the Yoruba name 'Derin' meaning 'Patience'. It's a unique and distinctive name, often shortened to Dere or Reginald. The name suggests someone who is calm and patient, but also strong-willed.
The name Dereginald had a single year of popularity with five births recorded in 1990, making it quite rare outside of that specific year.