Nastacia is of Slavic origin, derived from the Greek name Anastasia, which means "resurrection". This name has been used among various Slavic cultures for centuries and was popularized by early Christian martyrs named Anastasia. In some languages, such as Polish and Russian, Nastacia is considered a distinct name rather than simply a variant of Anastasia. It is often associated with beauty and grace due to its etymological roots.
The name Nastacia experienced peak popularity in 1988 with 14 births that year, while the least popular years were 1994, 1996, and 1998 with only 6 births each. Overall, there have been a total of 136 babies named Nastacia between 1984 and 2005.