Crixus is of Latin origin, derived from the Roman family name Crexus. It is composed of two elements: 'crinis', meaning 'hair', and '-us', a suffix indicating belonging to or connected with. Therefore, Crixus could be interpreted as 'of the hair' or 'belonging to hair'. This name was not particularly common in ancient Rome, but it gained some recognition through its use by historical figures such as the gladiator Spartacus's lieutenant, also named Crixus.
The name Crixus has seen a rise and fall in popularity over the years, with peak birth years being 2014 (26 births) and 2017 (25 births), followed by a steady decline to only 8 births recorded in 2023.