Keyondre is of African American origin, derived from the combination of "key" and "Andre". It means "manly" or "strong man", reflecting its roots as an African name. This unique name gained popularity in the United States during the late 20th century.
"The name Keyondre experienced a significant peak in popularity from 2004 to 2008, with the highest number of births occurring in 2008 at 46. However, its usage has been relatively consistent over time, fluctuating between 5 and 22 births per year since then."