Kwesi is of Ghanaian origin, meaning "born on Saturday" in the Akan language. It is traditionally given to boys born on that day according to the Akan calendar. This name reflects the cultural significance attached to the day of birth among the Akan people and adds a unique touch when chosen for its meaning rather than simply its sound.
The name Kwesi has seen varied popularity over the years, with peaks in the late 1970s and early 1990s, and a steady decline since the mid-2000s. The total number of babies named Kwesi between 1971 and 2023 is 800.