Oluwatomisin is of Nigerian origin, derived from the Yoruba culture. It consists of two elements: "Oluwa", which means "owner" or "lord", and "Tomisin", meaning "let us make it prosper". Thus, the name Oluwatomisin translates to "May God make it prosper". This name reflects the strong cultural beliefs and faith in divine intervention among the Yoruba people. It is often shortened to Tomi for everyday use but maintains its full form for formal or ceremonial occasions.
The name Oluwatomisin experienced variable popularity over the given years, with a noticeable peak in 2004 and another high point in 2015. The total number of births bearing this name over the period was 131.