Jeffrie is of American origin and is a variant spelling of Jeffrey, which is derived from the Middle English name Geoffrey. The name means "peaceful" or "god's peace". It gained popularity in the United States during the mid-20th century.
The name Jeffrie experienced its peak popularity in the mid-20th century, with a significant number of births occurring annually between 1952 and 1961. The highest recorded year was 1961, with 45 births. However, the popularity of the name has since declined steadily, with fewer than 10 births per year occurring from the late 1980s onwards. Overall, there have been a total of 934 births named Jeffrie between 1921 and 2017.