Karlisa is an uncommon female given name of American origin, derived from combining elements of Karl (a German form of Charles) and Lisa (short for Elizabeth). It means "strong" or "free man", reflecting the strength and independence often associated with its components.
The name Karlisa experienced fluctuations in popularity between 1972 and 1998, with the highest number of births occurring in 1993 at 12, and a low point in 1972 with only 5 births. The total number of babies named Karlisa during this period was 120.