Arsenio is a name of Spanish origin, derived from the Latin word 'arsenius', which means 'virile' or 'masculine'. It is composed of the elements 'arsen-' meaning 'male' and '-eus' as a suffix denoting belonging to or having the qualities of. The name was popularized during the Middle Ages through Saint Arsenius, who was a Christian martyr and bishop of Orleans in the 4th century. In Spanish-speaking countries, Arsenio is often used as a given name, and its variants include Arseni and Arsene.
The name Arsenio experienced a notable increase in popularity from the late 1980s onwards, with significant spikes in birth years 1987 (83 births), 1988 (124 births), and 1989 (397 births). Before this period, the annual count of births named Arsenio consistently remained under 20. Since peaking in 1989, the popularity of the name has fluctuated but generally declined, with fewer than 25 births per year from 1990 onwards, except for occasional spikes such as in 2008 (24 births) and 2023 (22 births). Overall, there have been a total of 2175 births registered with the name Arsenio since 1913.