Mikeisha is of African American origin, derived from the Arabic name Michael, which means "who is like God?" It has been popular among Americans since the mid-20th century, often favored for its distinctive sound and association with popular culture. The name Mikeisha was particularly common in the United States during the 1970s and 1980s but remains a unique choice today. It is commonly spelled with an 'i' before the 's', but variations such as Mikaisha, Mixieasha, or Mikaesha can also be found. Despite its African American roots, Mikeisha has been embraced by diverse communities worldwide, reflecting the global appeal of names derived from classic favorites like Michael.
"Mikeisha experienced peak popularity in the early 1990s with 20 births in 1992 and 21 births in 1994. However, its usage has significantly declined since the late 1990s, with fewer than 10 births per year from 1997 onwards."