Effrem is of Hebrew origin, derived from the word 'efrayim', which means 'fruitful'. It's the name of one of the sons of Joseph and Asenath in the Book of Genesis. Effrem was traditionally used as a male given name but has also been used for females in some cultures. In the late 19th and early 20th centuries, it was occasionally used among Ashkenazi Jews.
"Effrem was quite popular as a baby boy name in the late 1950s and early 1970s, with peaks of popularity in 1959 (9 births) and then again in intervals of ten years later - 1961, 1971, and 1974 (each with 5 births). Altogether, there were 24 babies named Effrem during this period."